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Interestingly, the 2 Pri-PCa was characterized by high levels of KLK3 and ERG but lack of KRT5 and KRT14 expression whereas the 3 CRPC samples all lacked KRT5 , KRT14 and ERG expression and 2 of the 3 CRPC (i.e., CRPC1 and mCRPC) showed high KLK3 expression (supplementary Fig